GLP-1 receptors are expressed in the heart muscle cells, immune system cells in the heart, and in the lining of blood vessels.[ref] GLP-1 RAs have been shown to help in heart failure and also to have beneficial effects on heart rhythm.[ref] Related article : Cardiovascular disease genetic risk factors Cancer Research: Retatrutide, a GLP-1/GIP/GCG triple agonist, has recently been shown to reduce pancreatic tumor mass in animals
however, 32% and 41% of patients in the semaglutide 2mg arm did not achieve an HbA1c target of less than 7% and weight loss of at least 5%, respectively
If nausea is severe or persistent, speak to your prescriber, as they may recommend delaying your dose escalation
Managing nausea can be disruptive and distressing
Additionally, semaglutide GLP-1 slows down the rate at which your stomach empties after eating, which contributes to a decrease in appetite and caloric intake
But this is not the case with semaglutide or any other GLP-1 drug